Gaziantep University

GAZİANTEP UNIVERSITY

Türkçe
Prof.Dr. EMİNE ELÇİN (ORUÇ) EMRE
HOMEPAGEDEPARTMENT OF CHEMISTRY
Publications
International Journals
Year
Content
2017
Journal / Book Name: Journal of Molecular Structure
No/Edition: 1149, 632-639
Authors: Kurşun-Aktar S., Oruç-Emre E.E., Demirtaş İ., Şahin-Yağlıoğlu A., Güler Ç., Adem Ş., Karaküçük-İyidoğan A.

Synthesis of novel fluorinated chalcones derived from 4'- morpholinoacetophenone and their antiproliferative effects.

2017
Journal / Book Name: Journal of The Chinese Chemical Society
No/Edition: 64, 321-330
Authors: Yıldız  I.N., Oruç-Emre E. E., Taşdemir D.,  Karaküçük-İyidoğan A., Ulaşlı M., Bayram H.

Design and Synthesis of Novel Thioureas Derived from 4-(4-Fluorophenoxy)aniline

as Anticancer Agents.

2017
Journal / Book Name: Phosphorus, Sulfur, and Silicon and the Related Elements
No/Edition: 192(7), 856-865
Authors: Kanmazalp S.D., Başaran E., Karaküçük-Iyidoğan A., Oruç-Emre E. E., Dege N.

X-ray Structures and Spectroscopic Properties of Chiral Thiosemicarbazides as Studied by Computational Calculations.

2017
Journal / Book Name: Marmara Pharmaceutical Journal
No/Edition: 21(4), 949-960
Authors: Kurşun-Aktar B.S., Oruç-Emre E.E., Karaküçük- İyidoğan A., Şahin Yağlıoğlu A., Demirtaş İ., Tekin Ş.

Synthesis and structure-activity relationship study: Anticancer chalcones derived from 4′-morpholinoacetophenone.

2016
Journal / Book Name: European Journal of Medicinal Chemistry
No/Edition: 270-283
Authors: Karaman N., Sıcak Y., Taşkın-Tok T., Öztürk M., Karaküçük-İyidoğan A., Dikmen M., Koçyiğit-Kaymakçıoğlu B., Oruç- Emre E. E.

New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors.

2016
Journal / Book Name: Chirality
No/Edition: 28, 495-513
Authors: Başaran E., Karaküçük-İyidoğan A., Schols D., Oruç-Emre E. E.

Synthesis of novel chiral sulfonamide-bearing 1,2,4-triazole-3-thione analogs derived from D and L-phenylalanine esters as potential anti-influenza agents

2016
Journal / Book Name: Medicinal Chemistry Research
No/Edition: 25, 1590-1607
Authors: Karaman N., Oruç-Emre E. E., Sıcak Y., Çatıkkaş B., Karaküçük-İyidoğan A., Öztürk M.

Microwave-assisted synthesis of new sulfonyl hydrazones, screening of biological activities and investigation of structure-activity relationship.

2015
Journal / Book Name: Chirality
No/Edition: 27, 177–188
Authors: Taşdemir D., Karaküçük-İyidoğan A., Ulaş M., Taşkın-Tok T., Oruç-Emre E.E.,  Bayram H.

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Chiral Thiosemicarbazone Derivatives as Potent Anticancer Agents.

2014
Journal / Book Name: Journal of the American Oil Chemists' Society
No/Edition: 91, 169-177
Authors: Büyükbeşe D., Oruç-Emre E.E., Kaya A.

Supercritical Carbon Dioxide Fractionation of Anhydrous Milk Fat.

2014
Journal / Book Name: Phosphorus, Sulfur, and Silicon and the Related Elements
No/Edition: 189, 661-669
Authors: Karaküçük-İyidoğan A., Mercan Z., Oruç-Emre E.E., Taşdemir D., İsler D., Kılıc İ.H., Özaslan M.

Synthesis, characterization and biological evaluation of some novel thiosemicarbazones as possible antibacterial and antioxidant agents.

2013
Journal / Book Name: Pest Management Science
No/Edition: 69, 703-708
Authors: Tabanca N., Ali A., Bernier U.R., Khan I.A., Koçyiğit-Kaymakçıoğlu B., Oruç-Emre E.E., Ünsalan S., Rollas S.

Biting Deterrence and Insecticidal activity of hydrazide-hydrazones and their corresponding 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazoles against Aedes aegypti.

2012
Journal / Book Name: Medicinal Chemistry Research
No/Edition: 21, 3499-3508
Authors: Koçyiğit-Kaymakçıoğlu, B., Oruç-Emre, E.E., Unsalan, S., Tabanca N., Khan S.I., Wedge D.E., Işcan G., Demirci F., Rollas, S.

Synthesis and biological activity of hydrazide–hydrazones and their corresponding 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazoles.

2011
Journal / Book Name: European Journal of Medicinal Chemistry
No/Edition: 46, 5616-5624
Authors: Karaküçük-İyidoğan A., Taşdemir D., Oruç-Emre E.E., Balzarini J.

Novel platinum(II) and palladium(II) complexes of thiosemicarbazones derived from 5-substitutedthiophene-2-carboxaldehydes and their antiviral and cytotoxic activities.

2011
Journal / Book Name: Medicinal Chemistry Research
No/Edition: 20 (5), 607-614
Authors: Kocyigit-Kaymakcioglu B. , Aker R.G., Tezcan K., Sakalli E., Ketenci S., Oruç-Emre E.E., Akin D., Gurbanova A., Terzioglu B., Onat F., Rollas S.

Anticonvulsant activity of 3,5-dimethylpyrazole derivatives in animal models.

2009
Journal / Book Name: Medicinal Chemistry Research
No/Edition: 18, 277-286
Authors: Koçyiğit-Kaymakçıoğlu, B., Oruç, E.E., Unsalan, S., Rollas, S.

Antituberculosis activity of hydrazones derived from 4-fluorobenzoic acid hydrazide.

2006
Journal / Book Name: Journal of Chromatography B
No/Edition: 831(1-2), 184-189
Authors: Kaymakçıoğlu-Koçyiğit B., Oruç E.E., Ünsalan S, Kabasakal L., Rollas S.
High- pressure liquid chromatographic analysis for identification of in vitro and in vivo metabolites of 4-phenylethyl-5-[4-(1-(2-hydroxyethyl)-3,5-dimethyl-4-pyrazolylazo)phenyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione in rats
2006
Journal / Book Name: Archiv der Pharmazie-Chemistry in Life Sciences
No/Edition: 339, 267-272
Authors: Oruç E.E., Kaymakçıoğlu-Koçyiğit B., Oral B., Altunbaş-Toklu H.Z., Kabasakal L.,
Synthesis of some novel azo derivatives of 3,5-dimethyl-1-(2- hydroxyethyl)pyrazole as potent analgesic agents
2006
Journal / Book Name: European Journal of Drug Metabolism and Pharmacokinetics
No/Edition: 31(1), 21-25
Authors: Oruc E.E., Unsal O., Balkan A., Ozkanli F., Gören M.Z., Terzioglu B., Rollas S.
The in vivo metabolism of 3-oxo-5-benzylidene-6-methyl-(4H)-2-(benzoylmethyl) pyridazine in rats
2006
Journal / Book Name: Pharmazie
No/Edition: 61(10), 823-827
Authors: Oruç EE,Kaymakçıoğlu-Koçyiğit B,Demircan FY,Gürbüz Y,Kalaça S,KüçükgüzelGŞ, Ül

An high performance liquid chromatographic method for the quantification of cotinine in the urine of preschool children

2006
Journal / Book Name: European Journal of Medicinal Chemistry
No/Edition: 41(11), 1253-1261
Authors: Koçyiğit-Kaymakçıoğlu B,Oruc E,Unsalan S,Kandemirli F,Shvets N,Rollas S,DimogloA

Synthesis and characterization of novel hydrazide–hydrazones and the study of their structure–antituberculosis activity

2004
Journal / Book Name: Journal Medicinal Chemistry
No/Edition: 47 (27), 6760-6767
Authors: Oruç E.E., Rollas S., Kandemirli F., Shvets N., Dimoglo A.S.
The 1,3,4-Thiadiazole derivatives synthesis, structure elucidation and structure-antituberculosis activity relationships ınvestigation.
2003
Journal / Book Name: European Journal of Drug Metabolism and Pharmacokinetics
No/Edition: 28(2), 113-118
Authors: Oruç E.E., Kabasakal L., Rollas S.
The in vivo metabolism of 5-(4-nitrophenyl)-4-(2-phenylethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione in rats.
2003
Journal / Book Name: Current Topics in Medicinal Chemistry,
No/Edition: 3, 135-151
Authors: Rollas S., Oruç E.E.
The Synthesis and biological activity of 1,3,4-thiadiazoles.
2002
Journal / Book Name: European Journal of Medicinal Chemistry
No/Edition: 37(3), 197-206
Authors: Kücükgüzel S.G., Oruç E.E., Rollas S., Şahin F., Özbek A.
Synthesis, characterisation and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds.
2000
Journal / Book Name: European Journal of Drug Metabolism and Pharmacokinetics
No/Edition: 25(2), 103-108
Authors: Gülerman N.N., Oruç E.E., Kartal F., Rollas S.
In vivo metabolism of 4-fluorobenzoic acid [(5-nitro-2-furanyl)methylene] hydrazide in rats
1999
Journal / Book Name: Drug Metabolism and Drug Interaction
No/Edition: 15(2-3), 127-140
Authors: Oruç E.E., Rollas S., Kabasakal L., Uysal M.K.
The in vivo metabolism of 5-(4-nitrophenyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione in rats
1999
Journal / Book Name: Drug Metabolism and Drug Interaction
No/Edition: 15(2-3), 107-114
Authors: Kaymakçıoğlu B., Oruç E., Ülgen M., Rollas S.
The in vitro hepatic microsomal metabolism of 3,5-dimethyl-4-(phenylazo)-(1H)-pyrazole in rats
Communications Presented and Published In a Book In The International Scientific Meetings
Year
Content
2005
Authors: Oruç E.E., Koçyiğit-KaymakçıoğluB., Oral B., Altunbaş-Toklu H.Z., Kabasakal L.
Synthesis of some novel azo derivatives of 3,5-dimethyl-1-(2-hydroxyethyl)pyrazole as potent analgesic agents. International Symposium on Medicinal Chemistry Research and Development, MCRD 2005, Poster P-21, Sempember 28-October 1, 2005, Kuşadası-Turkey.
2005
Authors: Koçyiğit-Kaymakçıoğlu B., Unsalan S., Oruç E.E., Rollas S.
Synthesis, characterization of novel hydrazide-hydrazones as potential antituberculosis agents. International Symposium on Medicinal Chemistry Research and Development, MCRD 2005, Poster P-22, Sempember 28-October 1, 2005, Kuşadası-Turkey.
2005
Authors: Kaymakçıoğlu KB,Oruç EE,YılmazF,GürbüzY,Kalaça S, Küçükgüzel ŞG,Ülgen M,RollasS
An high performance liquid chromatographic method for the quantification of cotinine in the urine of preschool children. International Symposium on Medicinal Chemistry Research and Development, MCRD 2005, Poster P-23, Sempember 28-October 1, 2005, Kuşadası-Turkey.
2004
Authors: Kaymakçıoğlu-Koçyiğit B., Oruç E.E., Ünsalan S, Kabasakal L., Rollas S.
The in vivo and in vitro metabolism of 4-phenylethyl-5-[4-(1-(2-hydroxyethyl)-3,5-dimethyl-4-pyrazolylazo)phenyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione. 2nd Inter- national Meeting and Pharmaceutical Chemistry, IMMPC-2, Poster P-79, 10-14 October 2004 Antalya-Turkey.
2003
Authors: Oruç E.E., Rollas S.
Synthesis and antituberculosis activity of some substituted 1,3,4-thiadiazole derivatives. 4th International Symposium on Pharmaceutical Chemistry, ISPC-4, Poster P-84, 17-19 Semptember 2003 Ankara-Turkey.
2002
Authors: Oruç E.E., Rollas S.
Synthesis and evaluation of some 1,3,4-thiadiazole derivatives. 1st International Meeting on Medicinal and Pharmaceutical Chemistry, IMMPC-1, Poster P-71, 25-28 Semptember 2002 Ankara-Turkey.
2000
Authors: Gülerman N.N., Oruç E.E., Kartal F., Rollas S.
In vivo metabolism of 4-fluorobenzoic acid [(5-nitro-2-furanyl)methylene]hydrazide in rats. 4th Xenobiotic Metabolism and Toxicity Workshop of Balkan Countries, Poster P-022, 12-16 April 2000 Antalya-Turkey.
2000
Authors: Oruç E.E., Rollas S., Kabasakal L.
The in vivo metabolism of 5-(4-nitrophenyl)-4-(2-phenylethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione in rats. 6th International Symposium on Pharmaceutical Science, ISOPS-6, Poster P-115, 27-29 June 2000 Ankara-Turkey.
2000
Authors: Kücükgüzel S.G., Rollas S., Oruç E.E.
Synthesis, characterization and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles. 6th International Symposium on Pharmaceutical Science, ISOPS-6, Poster P-141, 27-29 June 2000 Ankara-Turkey.
1999
Authors: Oruç E.E., Kücükgüzel S.G., Rollas S.
Synthesis, characterization of some novel hydrazones and thiosemicarbazides of 4-(4-methoxy-benzoylamino)benzoyl hydrazine. Second International Symposium on Pharmaceutical Chemistry, Poster P-04, 22-24 Semptember 1999 Ankara-Turkey.
1998
Authors: Kaymakçıoğlu B., Oruç E., Ülgen M., Rollas S.
The in vitro hepatic microsomal metabolism of 3,5-dimethyl-4-(phenylazo)-(1H)-pyrazole in rats. Second International Meeting on Pharmacy & Pharmaceutical Science, Poster P-72, 06-09 Semptember 1998 İstanbul-Turkey.
1998
Authors: Oruç E.E., Rollas S., Kabasakal L., Keyer-Uysal M.
The in vivo metabolism of 5-(4-nitrophenyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione in rats. Second International Meeting on Pharmacy & Pharmaceutical Science, Poster P-78, 06-09 Semptember 1998 İstanbul-Turkey.
1997
Authors: Oruç E.E., Rollas S.
The in vivo metabolism of 5-(4-nitrophenyl)-4-(2-phenylethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione in rats. First International Symposium on Pharmaceutical Chemistry, Oral contributions O-020, 24-26 Semptember 1997 Ankara-Turkey.
1997
Authors: Rollas S., Ünsalan S., Oruç E.E., Büyüktimin S.
Reductive cleavage of some compounds containing triazene functional group with hydrazine hydrate. First International Symposium on Pharmaceutical Chemistry, Poster P-029, 24-26 Semptember 1997 Ankara-Turkey.
National Journals
Year
Content
2015
Journal / Book Name: Marmara Üniversitesi Saglik Bilimleri Enstitüsü Dergisi MUSBED
No/Edition: 1(1):10-14
Authors: Mohsen, Usama A., Koçyigit-Kaymakçioglu, B., Oruç-Emre, E.E., Kaplancikli, Z.A., Rollas, S.
Studies on hydrazide-hydrazones derivatives as acetylcholinesterase inhibitor.
2014
Journal / Book Name: Caucasian Journal of Science
No/Edition: 1, 51-61
Authors: Büyükbeşe, D., Emre, E.E. ve Kaya, A.

Süt Yağı ve Fraksiyonlarının Özellikleri.

2011
Journal / Book Name: Anadolu Üniversitesi Bilim ve Teknoloji –Life Science and Biotechnology
No/Edition: 1 (2), 137-144
Authors: Koçyiğit-Kaymakçıoğlu, B, Oruç-Emre, E., Beyhan N., Toklu H.Z., Gümrü S.,  Arıcıoğlu, F.

Şalkonlardan Türetilen Bazı 2–Pirazolinlerin Sentezi ve Antikonvulsan Aktiviteleri.

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